Posts tagged virus

Engineered Stem Cells Seek out and Kill HIV in Living Mice.  Expanding on previous research providing proof-of-principal that human stem cells can be genetically engineered into HIV-fighting cells, a team of UCLA researchers have now demonstrated that these cells can actually attack HIV-infected cells in a living organism. The study, published April 12 in the journal PLoS Pathogens, demonstrates for the first time that engineering stem cells to form immune cells that target HIV is effective in suppressing the virus in living tissues in an animal model, said lead investigator Scott G. Kitchen, an assistant professor of medicine in the division of hematology and oncology at the David Geffen School of Medicine at UCLA and a member of the UCLA AIDS Institute. “We believe that this study lays the groundwork for the potential use of this type of an approach in combating HIV infection in infected individuals, in hopes of eradicating the virus from the body,” he said.  Read more here.

Engineered Stem Cells Seek out and Kill HIV in Living Mice.  Expanding on previous research providing proof-of-principal that human stem cells can be genetically engineered into HIV-fighting cells, a team of UCLA researchers have now demonstrated that these cells can actually attack HIV-infected cells in a living organism.

The study, published April 12 in the journal PLoS Pathogens, demonstrates for the first time that engineering stem cells to form immune cells that target HIV is effective in suppressing the virus in living tissues in an animal model, said lead investigator Scott G. Kitchen, an assistant professor of medicine in the division of hematology and oncology at the David Geffen School of Medicine at UCLA and a member of the UCLA AIDS Institute.

“We believe that this study lays the groundwork for the potential use of this type of an approach in combating HIV infection in infected individuals, in hopes of eradicating the virus from the body,” he said. 

Read more here.

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Virus-Cell Interaction Joerg SchroeerDepartment of Molecular Biology, Princeton Human cytomegalovirus infected human endothelial cells. Multicolor Immunofluorescence (IF). Blue: DAPI = cellular DNA. Green = GFP (green fluorescence protein). Red + Magenta = two different viral proteins. Captured with a Zeiss LSM510 laser scanning confocal microscope. See here for more photos from Princeton University’s 2005 Art of Science Competition.

Virus-Cell Interaction
Joerg Schroeer
Department of Molecular Biology, Princeton

Human cytomegalovirus infected human endothelial cells. Multicolor Immunofluorescence (IF). Blue: DAPI = cellular DNA. Green = GFP (green fluorescence protein). Red + Magenta = two different viral proteins. Captured with a Zeiss LSM510 laser scanning confocal microscope.
See here for more photos from Princeton University’s 2005 Art of Science Competition.

princeton.edu